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Scientific Schematics

K-DenseCommunityCreated by K-Dense Inc.

  • Skill
  • Content generator
  • Science and research
  • MIT
  • Low risk
  • Has scripts

From the author

Generates scientific diagram drafts using Nano Banana 2 AI with smart iterative refinement. Uses Gemini 3.7 Flash for quality review. Refines when the review requests improvement, with at most two generations. Specialized in neural network architectures, system diagrams, flowcharts, biological pathways, and complex scientific visualizations.
— the description by K-Dense Inc.

From the skill’s files

Taken from the skill’s own files (its description, section headings and stated usage). Not an AutoGineer summary, and not written by the author as one.

Generates scientific diagram drafts using Nano Banana 2 AI with smart iterative refinement. Uses Gemini 3.7 Flash for quality review. Refines when the review requests improvement, with at most two generations. Specialized in neural network architectures, system diagrams, flowcharts, biological pathways, and complex scientific visualizations. Scientific schematics and diagrams transform complex concepts into clear visual representations for publication. This skill uses Nano Banana 2 AI for diagram generation with Gemini 3.7 Flash quality review.

What it does

  • Overview
  • Quick Start: Generate Any Diagram
  • When to Use This Skill
  • How to Use This Skill
  • Smart Iterative Refinement, Advanced Usage, and Examples
  • Command-Line Usage

When to use it

  • Creating neural network architecture diagrams (Transformers, CNNs, RNNs, etc.)
  • Illustrating system architectures and data flow diagrams
  • Drawing methodology flowcharts for study design (CONSORT, PRISMA)
  • Visualizing algorithm workflows and processing pipelines
  • Creating circuit diagrams and electrical schematics
  • Depicting biological pathways and molecular interactions

Advantages

The skill’s files do not state this.

Usage examples

The skill’s files do not state this.

Install

  1. Download the skill as a ZIP:

    https://mp-staging.autogineer.com/agent-skills/k-dense-ai/scientific-schematics-tqw4/download
  2. Unzip it into the cross-client skills folder of your project:

    mkdir -p .agents/skills && unzip scientific-schematics.zip -d .agents/skills

Documentation by K-Dense Inc.

Scientific Schematics and Diagrams

Overview

Scientific schematics and diagrams transform complex concepts into clear visual representations for publication. This skill uses Nano Banana 2 AI for diagram generation with Gemini 3.7 Flash quality review.

How it works:

  • Describe your diagram in natural language

  • Nano Banana 2 generates a PNG draft from the specified components and relationships

  • Gemini 3.7 Flash reviews quality against document-type thresholds

  • Smart iteration: Refines when the score or verdict requests improvement

  • Saved drafts and a review log for manual verification

  • No coding, templates, or manual drawing required

Local review thresholds by document type (heuristics chosen by this helper, not publisher acceptance criteria):

Document TypeThresholdDescription
journal8.5/10Nature, Science, peer-reviewed journals
conference8.0/10Conference papers
thesis8.0/10Dissertations, theses
grant8.0/10Grant proposals
preprint7.5/10arXiv, bioRxiv, etc.
report7.5/10Technical reports
poster7.0/10Academic posters
presentation6.5/10Slides, talks
default7.5/10General purpose

Save diagrams under figures/ using -o figures/name.png, then inspect every label and relationship before including them in a paper or poster. The output location is the path you choose.

What the output is: a raster PNG at whatever resolution the image model returns. This skill has no vector path and no DPI control — if a journal demands PDF, EPS, or 300 dpi TIFF, convert the PNG downstream and check the result at final print size.

Quick Start: Generate Any Diagram

Run from this skill directory with requests installed and OPENROUTER_API_KEY set. The following paid-generation examples are illustrative; the request contracts are tested offline. Supply source-backed labels and relationships rather than asking the image model to invent them:

# Generate for journal paper (highest quality threshold: 8.5/10)
python scripts/generate_schematic.py "CONSORT participant flow diagram with 500 screened, 150 excluded, 350 randomized" -o figures/consort.png --doc-type journal

# Generate for presentation (lower threshold: 6.5/10 - faster)
python scripts/generate_schematic.py "Transformer encoder-decoder architecture showing multi-head attention" -o figures/transformer.png --doc-type presentation

# Generate for poster (moderate threshold: 7.0/10)
python scripts/generate_schematic.py "MAPK signaling pathway from EGFR to gene transcription" -o figures/mapk_pathway.png --doc-type poster

# Custom max iterations (max 2)
python scripts/generate_schematic.py "Complex circuit diagram with op-amp, resistors, and capacitors" -o figures/circuit.png --iterations 2 --doc-type journal

What happens behind the scenes:

  1. Generation 1: Nano Banana 2 creates initial image following scientific diagram best practices

  2. Review 1: Gemini 3.7 Flash evaluates quality against document-type threshold

  3. Decision: If quality >= threshold and no improvement verdict → DONE (no more iterations needed!)

  4. If below threshold or improvement requested: Improved prompt based on critique, regenerate

  5. Repeat: Until quality meets threshold OR max iterations reached

Smart Iteration Benefits:

  • ✅ Saves API calls if first generation is good enough

  • ✅ Higher quality standards for journal papers

  • ✅ Faster turnaround for presentations/posters

  • ✅ Appropriate quality for each use case

Output: Versioned images (name_v1.png, name_v2.png), a copy of the latest successful version at the path you asked for, and name_review_log.json with the score, critique, and any early-stop reason.

When the review cannot run — a rate limit, a content filter, a reviewer that answers in some unexpected shape — the image is still generated and saved, but no score is invented for it. The log records "score": null with the reason in "review_error". "reviewed": false means the reviewer did not return a usable response; a prose answer with no parsable score can have "reviewed": true. "final_reviewed" remains false without a numeric score, and the run prints Review unavailable - image kept, quality not verified. Treat that image as unchecked and look at it yourself and diagnose the review error before spending on another generation. A generation failure ends the loop without automatic replay; if an earlier draft exists, it is retained with its score and the failure in the log.

Configuration

Set your OpenRouter API key:

export OPENROUTER_API_KEY='your_api_key_here'

Get an API key at: https://openrouter.ai/keys

Data leaves the machine. Your prompt is sent to OpenRouter to generate the image, and the generated image is sent back to OpenRouter for the quality review. Both are subject to OpenRouter's data policies and those of the underlying model providers. Do not describe unpublished data, patient information, or anything under embargo in the prompt.

Current API contract

The image call uses OpenRouter POST /api/v1/images with model, prompt, and n: 1; it reads data[0].b64_json and checks the returned MIME type (when supplied) and PNG signature. Quality review separately uses POST /api/v1/chat/completions with text and an image_url data URL. Both use Bearer authentication. The current chat schema still allows image output; this helper follows the dedicated image-generation guide without assuming the chat route was retired.

Models are google/gemini-3.1-flash-image (Nano Banana 2) and google/gemini-3.7-flash (review). Their IDs and modalities were checked in public catalogs; this helper's Gemini generation/review calls were validated offline, not with a paid end-to-end run. See the verified contract and sources before changing models or request fields.

For trial flows, use the CONSORT 2025 template and item 22a, reconcile enrollment/allocation/follow-up/analysis counts, and report the specified primary outcome. For reviews, choose the appropriate PRISMA 2020 template; records, reports, and studies are distinct units. An AI score checks neither accounting system.

AI Generation Best Practices

Effective Prompts for Scientific Diagrams:

✓ Good prompts (specific, detailed):

  • "CONSORT flowchart showing participant flow from screening (n=500) through randomization to final analysis"

  • "Transformer neural network architecture with encoder stack on left, decoder stack on right, showing multi-head attention and cross-attention connections"

  • "Simplified EGFR → GRB2/SOS → RAS-GTP → RAF → MEK → ERK pathway; label nucleotide exchange and phosphorylation distinctly"

  • "Block diagram of IoT system: sensors → microcontroller → WiFi module → cloud server → mobile app"

✗ Avoid vague prompts:

  • "Make a flowchart" (too generic)

  • "Neural network" (which type? what components?)

  • "Pathway diagram" (which pathway? what molecules?)

Key elements to include:

  • Type: Flowchart, architecture diagram, pathway, circuit, etc.

  • Components: Specific elements to include

  • Flow/Direction: How elements connect (left-to-right, top-to-bottom)

  • Labels: Key annotations or text to include

  • Style: Any specific visual requirements

Scientific quality instructions (requested in the prompt; verify the result):

  • Clean white/light background

  • High contrast for readability

  • Clear, readable labels (minimum 10pt)

  • Professional typography (sans-serif fonts)

  • Colorblind-friendly colors (Okabe-Ito palette)

  • Proper spacing to prevent crowding

  • Scale bars, legends, axes where appropriate

When to Use This Skill

This skill should be used when:

  • Creating neural network architecture diagrams (Transformers, CNNs, RNNs, etc.)

  • Illustrating system architectures and data flow diagrams

  • Drawing methodology flowcharts for study design (CONSORT, PRISMA)

  • Visualizing algorithm workflows and processing pipelines

  • Creating circuit diagrams and electrical schematics

  • Depicting biological pathways and molecular interactions

  • Generating network topologies and hierarchical structures

  • Illustrating conceptual frameworks and theoretical models

  • Designing block diagrams for technical papers

How to Use This Skill

Simply describe your diagram in natural language. Nano Banana 2 generates it automatically:

python scripts/generate_schematic.py "your diagram description" -o output.png

The AI attempts:

  • ✓ Layout and composition

  • ✓ Labels and annotations

  • ✓ Colors and styling

  • ✓ Quality review and refinement

  • ✓ PNG output for visual and scientific verification

Works for all diagram types:

  • Flowcharts (CONSORT, PRISMA, etc.)

  • Neural network architectures

  • Biological pathways

  • Circuit diagrams

  • System architectures

  • Block diagrams

  • Any scientific visualization

No coding, no templates, no manual drawing required.


AI Generation Mode (Nano Banana 2 + Gemini 3.7 Flash Review)

Smart Iterative Refinement, Advanced Usage, and Examples

The generate-review-refine loop, the Python API and command-line options, prompt engineering guidance, and four worked examples (CONSORT flowchart, neural network architecture, biological pathway, system architecture) are in references/iterative_refinement.md.

The loop stops when the review passes or is unavailable, or when generation fails. A below-threshold score or an explicit improvement verdict can trigger a second generation; no run makes more than two attempts.

Command-Line Usage

The main entry point for generating scientific schematics:

# Basic usage
python scripts/generate_schematic.py "diagram description" -o output.png

# Custom iterations (max 2)
python scripts/generate_schematic.py "complex diagram" -o diagram.png --iterations 2

# Verbose mode
python scripts/generate_schematic.py "diagram" -o out.png -v

Review is advisory: the vision model can miss incorrect counts, topology, or labels. A high score does not establish scientific validity, CONSORT/PRISMA compliance, accessibility conformance, or a journal's acceptance of AI-generated figures.

Best Practices Summary

Design principles — ask for these in the prompt
  1. Clarity over complexity - Simplify, remove unnecessary elements

  2. Consistent styling - Describe the same visual conventions across a paper's figures

  3. Colorblind accessibility - Ask for the Okabe-Ito palette and redundant encoding

  4. Appropriate typography - Sans-serif fonts, generously sized labels

  5. Logical flow - State the direction (left-to-right, top-to-bottom) explicitly

The generator includes all of these as prompt instructions by default, but naming them in your own words for the specific diagram works better than relying on the built-in guidelines alone.

What the pipeline cannot do
  1. Vector output - PNG only; no PDF, SVG, or EPS is produced

  2. Resolution control - the image model chooses; there is no DPI flag

  3. Color space - RGB only; convert for CMYK print workflows downstream

  4. Exact line weights or text sizes - describe them in the prompt, then verify by eye

For raster submissions, check effective resolution as pixel width divided by final width in inches before converting to TIFF. Changing DPI metadata or enlarging pixels does not restore missing detail. Wrapping a PNG in PDF/EPS also leaves it raster: if the venue requires editable vector lines and text, redraw those elements with vector tools and verify their scientific content. Follow the venue's figure specifications.

Integration Guidelines
  1. Include in LaTeX - Use \includegraphics{} for generated images

  2. Caption thoroughly - Describe all elements and abbreviations

  3. Reference in text - Explain diagram in narrative flow

  4. Maintain consistency - Same style across all figures in paper

  5. Version control - Keep prompts and generated images in repository

Troubleshooting Common Issues

Generation is stochastic and iteration is capped at 2, so the levers that actually change the outcome are the prompt, the document type, and re-running. There is no post-processing step and no quality-checking library in this skill: everything you can inspect lives in the generated PNG and in <name>_review_log.json.

The diagram is wrong

Overlapping text, crowded elements, or arrows that miss their targets

  • Name the layout in the prompt: "vertical flow, one box per row, generous spacing between stages"

  • Name the connections: "arrow from RAF to MEK labelled phosphorylation", not "show the cascade"

  • Re-run. Two runs of the same prompt differ, and a bad layout is often just an unlucky draw

Content is scientifically wrong or a component is missing

  • List the components explicitly, with counts and labels — the model will not infer them

  • Read the critique field in the review log: the reviewer usually names what it saw missing

Wrong text in labels, or figure numbering baked into the image

  • The prompt already forbids "Figure 1:" captions; if one appears anyway, re-run

  • Misspelled labels are the most common failure of image models. Read every label before using it

The score seems wrong

Score is lower than the diagram deserves

  • Read the critique before re-running; the reviewer's complaint is often legitimate and specific

  • The threshold, not the score, decides whether it iterates — --doc-type journal demands 8.5

A run stops at a score below the threshold

  • That can be the iteration cap or a failed second generation. --iterations 2 is the maximum; the latest successfully generated image is kept with its real score. Check termination_reason and each attempt's error.

"score": null and "reviewed": false in the log

  • The review call failed or answered in an unusable shape. The image was kept but its quality is unknown. Check "review_error" and inspect the image yourself.

Setup

Error: OPENROUTER_API_KEY not found

  • export OPENROUTER_API_KEY='sk-or-v1-...', or add it to a .env file, or pass --api-key

Error: requests library not found

  • uv pip install requests

Any API error — run with -v to see the route, model slug, and a bounded error message. A 401/402 needs credential/credit correction; a timeout does not justify blind paid replay.

Resources and References

Detailed References

Load these files for comprehensive information on specific topics:

  • references/iterative_refinement.md - The generate-review-refine loop, the Python API, every command-line option, prompt engineering guidance, and four worked examples

  • references/best_practices.md - Publication standards and accessibility guidelines to draw on when writing prompts and when judging the result

External Resources

Publication Standards

Integration with Other Skills

This skill works synergistically with:

  • Scientific Writing - Diagrams follow figure best practices

  • Scientific Visualization - Shares color palettes and styling

  • LaTeX Posters - Generate diagrams for poster presentations

  • Research Grants - Methodology diagrams for proposals

  • Peer Review - Evaluate diagram clarity and accessibility

Quick Reference Checklist

Before submitting diagrams, verify:

Read the review log (this is the only automated check there is)
  • [ ] <name>_review_log.json exists; inspect the successful iteration named by "final_image" (a later attempt may have failed)

  • [ ] "final_reviewed" and "quality_met" are true, then inspect the critique and image yourself

  • [ ] Read the "critique" — the reviewer's remaining issues are listed even on a passing score

  • [ ] If more than one version was generated, compare _v1 and _v2 and keep the better one

Look at the image yourself
  • [ ] Every label is spelled correctly — image models misspell text, and no automated check here catches it

  • [ ] No overlapping or clipped text

  • [ ] All arrows connect the elements they are meant to connect

  • [ ] The science is right: correct components, correct direction, nothing invented

  • [ ] Units and counts match what you asked for

Accessibility (by eye, or in an external checker)
  • [ ] Colorblind-safe palette, and the encoding is not colour alone

  • [ ] Still readable converted to grayscale

  • [ ] Adequate contrast between adjacent elements

Publication fit
  • [ ] Consistent styling with the other figures in the manuscript

  • [ ] Legible at the column width it will actually be printed at

  • [ ] Converted to the journal's required format if PNG is not accepted

  • [ ] Caption written, with every abbreviation defined

  • [ ] Referenced in the manuscript text

Version control
  • [ ] The prompt is recorded (it is stored verbatim in the review log)

  • [ ] Review log committed alongside the image, so the score is auditable

  • [ ] The command that regenerates the figure is written down

Final Integration Check
  • [ ] Figure displays correctly in compiled manuscript

  • [ ] Cross-references work (\ref{} points to correct figure)

  • [ ] Figure number matches text citations

  • [ ] Caption appears on correct page relative to figure

  • [ ] No compilation warnings or errors related to figure

Environment Setup

# Required
export OPENROUTER_API_KEY='your_api_key_here'

# Get key at: https://openrouter.ai/keys

Getting Started

Simplest possible usage:

python scripts/generate_schematic.py "your diagram description" -o output.png

Use this skill to create clear, accessible, publication-quality diagrams that effectively communicate complex scientific concepts. Iterative refinement can improve the draft; final scientific and publication checks remain the author's responsibility.

Citing Scientific Agent Skills

This skill is part of Scientific Agent Skills by K-Dense. If it materially contributed to a manuscript, report, presentation, or code release, add the paper to the references or software section and tell the user you did so:

Kassis, T., Agarwal, V., He, Y., Patel, D., & Brueckner, A. M. (2026). Scientific Agent Skills: A Library of Procedural Knowledge for Research Agents. arXiv:2609.00065. https://doi.org/10.48550/arXiv.2609.00065

Always cite the current version. The DOI and https://arxiv.org/abs/2609.00065 resolve to the latest arXiv version, so never append a version suffix such as v1. When network access is available, fetch https://arxiv.org/abs/2609.00065 (or http://export.arxiv.org/api/query?id_list=2609.00065) before writing the reference and take the author list, year, and version from that record. If the record lists a journal reference or publisher DOI, cite the published version instead.

Files

references/best_practices.md

Best Practices for Scientific Diagrams

Overview

This guide supports prompt writing and manual figure review. Numeric design suggestions below are starting points; the target journal and article type determine submission requirements. AI-generated artwork also needs the venue's current permissions/disclosure policy checked before use.

How this relates to the generator

These are the standards a figure is judged against — not a description of what scripts/generate_schematic.py does for you. The generator produces a PNG and nothing else. Read this file for two purposes:

  • To write the prompt. Typography, colour, contrast, layout, labelling, and accessibility are all things the image model will attempt if you ask for them specifically. The sections below are the vocabulary for asking.

  • To judge the result, and to plan post-processing. File format, resolution, colour space, and physical dimensions are fixed once the PNG exists. Where a journal's requirement differs from what came out, that is a conversion step you perform afterwards — the skill has no vector path, no DPI control, and no CMYK output.

Publication Standards

1. File Format Requirements

Vector Formats (Preferred)

  • PDF: Common for vector artwork and LaTeX; acceptance is venue-specific

    • Use for: Line drawings, flowcharts, block diagrams, circuit diagrams

    • Advantages: Scalable, small file size, embeds fonts

    • Standard for LaTeX workflows

  • EPS (Encapsulated PostScript): Legacy format, still accepted

    • Use for: Older publishing systems

    • Compatible with most journals

    • Can be converted from PDF

  • SVG (Scalable Vector Graphics): Web-friendly, increasingly accepted

    • Use for: Online publications, interactive figures

    • Can be edited in vector graphics software

    • Not all journals accept SVG

Raster Formats (When Necessary)

  • TIFF: Professional standard for raster graphics

    • Use for: Microscopy images, photographs combined with diagrams

    • Minimum 300 DPI at final print size

    • Lossless compression (LZW)

  • PNG: Web-friendly, lossless compression

    • Use for: Online supplementary materials, presentations

    • Minimum 300 DPI for print

    • Supports transparency

Avoid for new diagram masters

  • JPEG: Lossy compression can damage text and lines; some venues accept high-quality JPEG for photographs

  • GIF: Limited colors, inappropriate for scientific figures

  • BMP: Uncompressed, unnecessarily large files

2. Resolution Requirements

Vector Graphics

  • Infinite resolution (scalable)

  • Recommended: Always use vector when possible

Raster graphics

  • Calculate effective pixels per inch at the final physical size.

  • Photographic submission targets commonly start at 300 ppi; line art may require more.

  • Screen quality depends on pixel dimensions and display size, not DPI metadata.

  • Check the venue-specific requirement before exporting; changing DPI metadata or upsampling cannot recover missing detail.

Calculating DPI

DPI = pixels / (inches at final size)

Example:
Image size: 2400 × 1800 pixels
Final print size: 8 × 6 inches
DPI = 2400 / 8 = 300 ✓ (acceptable)
3. Size and Dimensions

Choose the venue and article type first

  • Nature's main-figure guide lists 89 mm and 183 mm widths; Extended Data has separate rules.

  • Other publishers have different width ranges and file requirements. Do not reuse Nature dimensions for Science, Cell, PLOS, or IEEE without checking that venue's current instructions.

  • See the source links under Journal-Specific Guidelines below.

Best Practices

  • Design at final print size (avoid scaling)

  • Use journal templates when available

  • Allow margins for cropping

  • Test appearance at final size before submission

4. Typography Standards

Font Selection

  • Recommended: Arial, Helvetica, Calibri (sans-serif)

  • Acceptable: Times New Roman (serif) for mathematics-heavy

  • Avoid: Decorative fonts, script fonts, system fonts that may not embed

Font Sizes (at final print size)

  • Minimum: 6-7 pt (journal dependent)

  • Axis labels: 8-9 pt

  • Figure labels: 10-12 pt

  • Panel labels (A, B, C): 10-14 pt, bold

  • Main text: Should match manuscript body text

Text Clarity

  • Use sentence case: "Time (seconds)" not "TIME (SECONDS)"

  • Include units in parentheses: "Temperature (°C)"

  • Spell out abbreviations in figure caption

  • Avoid rotated text when possible (exception: y-axis labels)

  • No figure numbers in diagram - do not include "Figure 1:", "Fig. 1", etc. (these are added by LaTeX/document)

5. Line Weights and Strokes

Recommended Line Widths

  • Diagram outlines: 0.5-1.0 pt

  • Connection lines/arrows: 1.0-2.0 pt

  • Emphasis elements: 2.0-3.0 pt

  • Minimum visible: 0.25 pt at final size

Consistency

  • Use same line weight for similar elements

  • Vary line weight to show hierarchy

  • Avoid hairline rules (too thin to print reliably)

Accessibility and Colorblindness

1. Colorblind-Safe Palettes

Okabe-Ito Palette (Recommended) A useful starting palette from Color Universal Design; no palette guarantees accessibility for every viewer, background, or adjacent pair:

% RGB values
Orange:     #E69F00 (230, 159,   0)
Sky Blue:   #56B4E9 ( 86, 180, 233)
Green:      #009E73 (  0, 158, 115)
Yellow:     #F0E442 (240, 228,  66)
Blue:       #0072B2 (  0, 114, 178)
Vermillion: #D55E00 (213,  94,   0)
Purple:     #CC79A7 (204, 121, 167)
Black:      #000000 (  0,   0,   0)

Alternative: ColorBrewer Palettes

  • Qualitative: consider Set2, Paired, Dark2 after enabling ColorBrewer's colorblind-safe filter for the chosen number of categories

  • Sequential: Blues, Greens, Oranges (avoid Reds/Greens together)

  • Diverging: RdBu (Red-Blue), PuOr (Purple-Orange)

Colors to Avoid Together

  • Red-Green combinations without redundant labels or shapes

  • Blue-Purple combinations

  • Yellow-Light green combinations

2. Redundant Encoding

Don't rely on color alone. Use multiple visual channels:

Shape + Color

Circle + Blue   = Condition A
Square + Orange = Condition B
Triangle + Green = Condition C

Line Style + Color

Solid + Blue = Treatment 1
Dashed + Orange = Treatment 2
Dotted + Green = Control

Pattern Fill + Color

Solid fill + Blue = Group A
Diagonal stripes + Orange = Group B
Cross-hatch + Green = Group C
3. Grayscale Compatibility

Test Requirement: All diagrams must be interpretable in grayscale

Strategies

  • Use different shades (light, medium, dark)

  • Add patterns or textures to filled areas

  • Vary line styles (solid, dashed, dotted)

  • Use labels directly on elements

  • Include text annotations

Grayscale Test

# Convert to grayscale to test
magick diagram.png -colorspace Gray diagram_gray.png
4. Contrast Requirements

WCAG 2.2 web accessibility targets (useful checks, not a blanket journal certification)

  • Normal text: 4.5:1

  • Large text (at least 18 pt regular or 14 pt bold): 3:1

  • Necessary graphical objects: 3:1 against adjacent colors, subject to the criterion's exceptions

See text contrast and non-text contrast. Raster labels still need to be legible at their final displayed size.

High Contrast Practices

  • Dark text on light background (or vice versa)

  • Avoid low-contrast color pairs (yellow on white, light gray on white)

  • Use black or dark gray for critical text

  • White text on dark backgrounds needs larger font size

5. Alternative Text and Descriptions

Figure Captions Must Include

  • Description of diagram type

  • All abbreviations spelled out

  • Explanation of symbols and colors

  • Sample sizes (n) where relevant

  • Statistical annotations explained

  • Reference to detailed methods if applicable

Example Caption "Participant flow diagram following CONSORT guidelines. Rectangles represent study stages, with participant numbers (n) shown. Exclusion criteria are listed beside each screening stage. In this illustrative complete-case example, primary-outcome analysis included n=325 participants (160 and 165); 25 lacked primary-outcome measurements. Reconcile this with the statistical analysis plan rather than equating every follow-up loss with exclusion from intention-to-treat analysis."

Design Principles

1. Simplicity and Clarity

Occam's Razor for Diagrams

  • Remove every element that doesn't add information

  • Simplify complex relationships

  • Break complex diagrams into multiple panels

  • Use consistent layouts across related figures

Visual Hierarchy

  • Most important elements: Largest, darkest, central

  • Supporting elements: Smaller, lighter, peripheral

  • Annotations: Minimal, clear labels only

2. Consistency

Within a Figure

  • Same shape/color represents same concept

  • Consistent arrow styles for same relationships

  • Uniform spacing and alignment

  • Matching font sizes for similar elements

Across Figures in a Paper

  • Reuse color schemes

  • Maintain consistent node styles

  • Use same notation system

  • Apply same layout principles

3. Professional Appearance

Alignment

  • Use grids for node placement

  • Align nodes horizontally or vertically

  • Evenly space elements

  • Center labels within shapes

White Space

  • Don't overcrowd diagrams

  • Leave breathing room around elements

  • Use white space to group related items

  • Margins around entire diagram

Polish

  • No jagged lines or misaligned elements

  • Smooth curves and precise angles

  • Clean connection points

  • No overlapping text

Common Pitfalls and Solutions

Pitfall 1: Overcomplicated Diagrams

Problem: Too much information in one diagram Solution:

  • Split into multiple panels (A, B, C)

  • Create overview + detailed diagrams

  • Move details to supplementary figures

  • Use hierarchical presentation

Pitfall 2: Inconsistent Styling

Problem: Different styles for same elements across figures Solution:

  • Create and use style templates

  • Use the same color palette throughout

  • Document your style choices

Pitfall 3: Poor Label Placement

Problem: Labels overlap elements or are hard to read Solution:

  • Place labels outside shapes when possible

  • Use leader lines for distant labels

  • Rotate text only when necessary

  • Ensure adequate contrast with background

Pitfall 4: Tiny Text

Problem: Text too small to read at final print size Solution:

  • Design at final size from the start

  • Test print at final size

  • Minimum 7-8 pt font

  • Simplify labels if space is limited

Pitfall 5: Ambiguous Arrows

Problem: Unclear what arrows represent or where they point Solution:

  • Use different arrow styles for different meanings

  • Add labels to arrows

  • Include legend for arrow types

  • Use anchor points for precise connections

Pitfall 6: Color Overuse

Problem: Too many colors, confusing or inaccessible Solution:

  • Limit to 3-5 colors maximum

  • Use color purposefully (categories, emphasis)

  • Stick to colorblind-safe palette

  • Provide redundant encoding

Quality Control Checklist

Before Submission

Technical Requirements

  • [ ] Correct file format (PDF/EPS preferred for diagrams)

  • [ ] Sufficient resolution (vector or 300+ DPI)

  • [ ] Appropriate size (matches journal column width)

  • [ ] Fonts embedded in PDF

  • [ ] No compression artifacts

Accessibility

  • [ ] Colorblind-safe palette used

  • [ ] Works in grayscale (tested)

  • [ ] Text minimum 7-8 pt at final size

  • [ ] High contrast between elements

  • [ ] Redundant encoding (not color alone)

Design Quality

  • [ ] Elements aligned properly

  • [ ] Consistent spacing and layout

  • [ ] No overlapping text or elements

  • [ ] Clear visual hierarchy

  • [ ] Professional appearance

Content

  • [ ] All elements labeled

  • [ ] Abbreviations defined

  • [ ] Units included where relevant

  • [ ] Legend provided if needed

  • [ ] Caption comprehensive

Consistency

  • [ ] Matches other figures in style

  • [ ] Same notation as text

  • [ ] Consistent with journal guidelines

  • [ ] Cross-references work

Journal-Specific Guidelines

Consult the current instructions for the exact journal and figure category. Avoid treating a local reviewer score or a single resolution value as a publication standard.

  • Nature final submission: main figures use 89/183 mm widths and editable vector artwork for line drawings where possible. Photographs need at least 300 dpi at use size. Extended Data has separate format/size rules. The figure guide recommends RGB and stresses that upsampling cannot improve detail.

  • PLOS ONE figures: TIFF/EPS, 300–600 dpi, and explicit width/height limits; inspect the current table rather than assuming generic single/double column widths.

  • IEEE graphics: use the current graphics guide for dimensions, format, resolution, fonts, and color handling. Do not assume all print editions are grayscale.

  • Science instructions and Cell author resources: exact dimensions and submission-stage rules must be checked for the manuscript. Science's and Cell's pages blocked automated access during this review; no numeric requirements are asserted here.

Scientific integrity before styling

Use source material for every entity, count, and relationship. For CONSORT 2025, distinguish allocation, receipt of intervention, discontinuation, follow-up, and the primary-outcome analysis set. For PRISMA 2020, reconcile records, reports, and studies using the appropriate template. A diagram should not invent omitted numbers or turn a missing outcome into an automatic analysis exclusion.

Software-Specific Export Settings

AI-Generated Images

AI-generated diagrams are exported as PNG images and can be included in LaTeX documents using:

\includegraphics[width=\textwidth]{diagram.png}
Python (Matplotlib) Export

Runnable local example, checked with Matplotlib 3.11.2. Install in a separate environment (uv run --no-project --isolated --with matplotlib==3.11.2 python example.py). This produces a schematic from explicit code; it does not vectorize a generated PNG.

import matplotlib
matplotlib.use('Agg')
import matplotlib.pyplot as plt

# Set publication quality
plt.rcParams['font.family'] = 'sans-serif'
plt.rcParams['font.sans-serif'] = ['DejaVu Sans']
plt.rcParams['font.size'] = 8
plt.rcParams['pdf.fonttype'] = 42  # TrueType fonts in PDF

fig, ax = plt.subplots(figsize=(3.5, 2.0))
ax.annotate('Input', (0.2, 0.5), ha='center', bbox={'boxstyle': 'round', 'fc': 'white'})
ax.annotate('Output', (0.8, 0.5), ha='center', bbox={'boxstyle': 'round', 'fc': 'white'})
ax.annotate('', (0.65, 0.5), (0.35, 0.5), arrowprops={'arrowstyle': '->'})
ax.set_axis_off()

# Save with proper DPI and cropping
fig.savefig('diagram.pdf', dpi=300, bbox_inches='tight', 
            pad_inches=0.1, transparent=False)
fig.savefig('diagram.png', dpi=300, bbox_inches='tight')
plt.close(fig)
Schemdraw Export

Checked with Schemdraw 0.23 and Matplotlib 3.11.2. Install schemdraw[matplotlib] in an isolated environment. The SVG backend alone cannot save PDF/PNG; choose the Matplotlib backend for this example. See the drawing API.

import matplotlib
matplotlib.use('Agg')
import schemdraw
import schemdraw.elements as elm

d = schemdraw.Drawing(canvas='matplotlib', show=False)
d += elm.Resistor().label('1 kΩ')
d += elm.Capacitor().down().label('10 µF')
d += elm.Ground()

# Export
d.save('circuit.svg')  # Vector
d.save('circuit.pdf')  # Vector
d.save('circuit.png', dpi=300)  # Raster
Inkscape Command Line

Current flags follow the Inkscape manual; the old --export-png and --export-pdf forms should not be used. These optional commands require Inkscape and were documentation-checked only.

# SVG to PNG (illustrative: Inkscape is not installed in the validation environment)
inkscape diagram.svg --export-type=png --export-filename=diagram.png --export-dpi=300

# SVG to PDF (preserves vector elements from the SVG)
inkscape diagram.svg --export-type=pdf --export-filename=diagram.pdf

Version Control Best Practices

Keep Source Files

  • Save original .tex, .py, or .svg files

  • Use descriptive filenames with versions

  • Document color palette and style choices

  • Include README with regeneration instructions

Directory Structure

figures/
├── source/          # Editable source files
│   ├── diagram1.tex
│   ├── circuit.py
│   └── pathway.svg
├── generated/       # Auto-generated outputs
│   ├── diagram1.pdf
│   ├── circuit.pdf
│   └── pathway.pdf
└── final/          # Final submission versions
    ├── figure1.pdf
    └── figure2.pdf

Git Tracking

  • Track source files (.tex, .py)

  • Consider .gitignore for generated PDFs (large files)

  • Use releases/tags for submission versions

  • Document generation process in README

Testing and Validation

Pre-Submission Tests

Visual Tests

  1. Print test: Print at final size, check readability

  2. Grayscale test: Convert to grayscale, verify interpretability

  3. Zoom test: View at 400% and 25% to check scalability

  4. Screen test: View on different devices (phone, tablet, desktop)

Technical Tests

  1. Font embedding: Check PDF properties

  2. Resolution check: Verify DPI meets requirements

  3. File size: Ensure under journal limits

  4. Format compliance: Verify accepted format

Accessibility Tests

  1. Colorblind simulation: Use tools like Color Oracle

  2. Contrast checker: WCAG contrast ratio tools

  3. Screen reader: Test alt text (for web figures)

Tools for Testing

Colorblind Simulation

  • Color Oracle (free, cross-platform)

  • Coblis (Color Blindness Simulator)

  • Photoshop/GIMP colorblind preview modes

PDF Inspection

Requires Poppler (pdfinfo, pdffonts, pdfimages) and ImageMagick 7 (magick). Embedded-image ppi from pdfimages -list differs from a PNG's density metadata; it reflects placement in that PDF.

# Check PDF properties
pdfinfo diagram.pdf

# Check fonts
pdffonts diagram.pdf

# Inspect embedded raster resolution in a PDF (Poppler)
pdfimages -list diagram.pdf

# Inspect pixel dimensions and density metadata of the generated PNG (ImageMagick 7)
magick identify -verbose diagram.png

Contrast Checking

Summary: Golden Rules

  1. Vector first: Always use vector formats when possible

  2. Design at final size: Avoid scaling after creation

  3. Colorblind-safe palette: Use Okabe-Ito or similar

  4. Test in grayscale: Diagrams must work without color

  5. Minimum 7-8 pt text: At final print size

  6. Consistent styling: Across all figures in paper

  7. Keep it simple: Remove unnecessary elements

  8. High contrast: Ensure readability

  9. Align elements: Professional appearance matters

  10. Comprehensive caption: Explain everything

Further Resources

Check the final artifact in its real manuscript layout; these checks support review but do not guarantee scientific correctness, accessibility, or publisher acceptance.

Requirements and compatibility

Works with: Claude Code, Claude apps, OpenAI Codex, GitHub Copilot, Cursor, Gemini CLI, Kiro, OpenCode, Goose, Amp, Roo Code, JetBrains Junie, Factory Droid, Devin (ex-Windsurf), Mistral Vibe, OpenHands, Letta

“Works with” means the tool reads the open Agent Skills format; a skill written for one tool may use features others lack.

Needs: Declares allowed tools, Needs network access, Needs an API key, Needs Python

The author says: Requires Python 3.10+ with requests, network access, and an OpenRouter API key.

Security

What our scanner noticed· Low risk

  • Instructions that use the network
  • Scripts that your agent may run

This skill includes scripts that your agent may run. Read them before you use it.

A static scan is not a guarantee. Skills are third-party content: review a skill before you let an agent use it.

Attribution and licence

Created by
K-Dense Inc.
Publisher
K-Dense (Community)
Source
K-Dense-AI/scientific-agent-skills · skills/scientific-schematics · commit a25cf9e
Licence
MIT License (redistribution allowed)
  • LICENSE (added by AutoGineer from LICENSE.md)
  • ATTRIBUTION.md (written by AutoGineer)
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